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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9592cdb1da032b3bff9f58b6f45cd63f176ec2b39ffb548b09870a85faaa8e2' 
  AND token = 'mw9VEzbaSH/mjYxQ/WVWYNIiHHlw41gRoIvMDAdU6ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}