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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca16a0ae47b04afba6ecc121354aa5646bad83854f0b4b31a5bf2de338be269f' 
  AND token = 'JgGzMwKQXG5g2i6u7RsSD7XoDLNoNl7yy0r5jsKJc8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}