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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760fb5e6d007b899c8c679ae3430b1dbbbe9a98eb23a65fde39edebc5b4e9194' 
  AND token = '/MZawCMFSzC+IGX/SxAdHO6d2eAkBIJc4n7yaxdYv6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}