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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8382b0cfc04a67453707855608196a94f1f9dd92d319d363d983e28c17a0ae25' 
  AND token = 'drDhO/XXe5+ActQYk/Eu4snR9aL8gBZG4DSY+CKgfT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}