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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c06c5e88a8a8e73cb6a5bfcfcbd83dd02f4637265d002de524fadc9449f8306' 
  AND token = '10Z75vhGz3P6N9qLItMWyvq4E/i3qE4T2+Q0f8Xqks4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}