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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07821122cd0e2d31182176223ebc90b137d257f6fafca56c1c7daf5c5a1050f' 
  AND token = 'HsEu4ImOhcLz9flt1O3pUkxS4a9UdvpgGnhuOSalQpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}