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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d47636c283b91ebfa43684a6e4ab0e01585e3883cf55a316f215904313b427' 
  AND token = '5MvIbTCM7ql2c+ipqPIAokJ562MP6B9XIvKWdqR8408=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}