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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72281924d3b9b5db25061c3854cf0f17257b8b6005d9f890735f63e9d1deccf5' 
  AND token = 'Casdh0C5YtQhRh6842lu4Xa22FhYXuI7e0mT+c2vf9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}