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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4bc1dd3579aa6dfc5142b9f5c6e4e929567431299925bb63987b3f56c827360' 
  AND token = 'uyLMawsdSQqnCSsrl/ewJimy6l6RjO2glDll2bJqF18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}