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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a50a47bef405e964348c89cea66efc33967124b7e6f6e44d4aec930a318eb07' 
  AND token = '1zGRJfSbtAADIR8v3wz4irX580iVhtD6RDuRSMyE/3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}