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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed5ab9b3b0863749f744072414278aad8271c2f3e78da77f417d38d8024009f' 
  AND token = 'r8UbNYWmpXHffoV77Ymh49fZSQdGqJRPaUYy3Nt1jgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}