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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c8955b1c3c5ffd1977277649820e06f3d8440df17a14e035f6c0f1996110f6' 
  AND token = 'opyndAKUOK+N4AgButhItt10Vv6pwkBhaIkS5MhIHpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}