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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79cd315fb3228674a57f651f2f0fa5b93faec2f9b403d5b395419ff2ff6363da' 
  AND token = 'VqA0O/4Y64N3qs4oYlHGmm2hZVxCZLuLDm57giECf1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}