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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be08d93cc0dfd0d352e62cd1b89e729a4dc8142f6c75fdd37581777e15f3fd49' 
  AND token = 'JELeCY9o0SToeAu2pvbR0kRNSBfuYzxuFItND19XO+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}