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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ce81a7ede61296a57d2b7e4f3e59e936ffbd96e0075969319b7ca934075860' 
  AND token = 'LckBbovFetbhIngygforlmJHJv9C489H4aqYTW3N2uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}