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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cd8285bb560b351c07b46440d7225a042ff9f11467c4dbb7b37657d160f6c4' 
  AND token = '5x3PYNa4cleDhyhqFlcqVl6TdfZRQ/H77hL5kHgsgCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}