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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f39bc8d4fde45e58ea1a648b31b05549f99a217993ff13592c6084258fc431a' 
  AND token = '1skxwXZBBzwqp0q772e41ONStgX3+NUSHCx4IHJAINM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}