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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e75b51e433f6a0efdc6502bf21ec694e0bc8a08d869e5e3b307e3eb8f0598c' 
  AND token = '41AAFXq/vcX6Kju8cL6GyMJPwe2Xb91U6lz2d4ZhyDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}