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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dca32a9bf183bac8643f7c5d650b27ac714ebcfb57b10ba4ad81dee645e5edba' 
  AND token = 'CEZnDstaCsxSh6d+/sJ0vMiK+dPB7iA2wXpXg5sxNus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}