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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc8323452ed9c44952b6f0c92031bad97a5b53bc6138a0591392bac787163f3' 
  AND token = '97u4PYGiB4NRls+lvy/2DTCPAozKXDKxBPySzOX27r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}