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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ad434e41d3160c1178ba22b7ae4121efe787ac75f245e14aeecbc3b29e6228' 
  AND token = 'qF6JAgqlBIFlkNypjm+DY00Qit9i+sJONS0Ef1yN/yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}