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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887e88fdff7a48cd495dcdf22ca85c5adc9f6b8f1d2c14301998288dd147d200' 
  AND token = '0VGmxbs19qXq/UquY5nJVAjJZCRVyxtkXT2o+uu1W9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}