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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a868fa673d744c6e2d003ad721c364588467344f0964a77c06e3f4045f0bfd14' 
  AND token = 'VsViOUADxMhcnuQFdtC5afT5oQnB3rZgK3qLbIQ+Qd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}