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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d4d70d490b4b0066faf6747a366dff0a06a1df4837cd526545b77ab60f3f61' 
  AND token = 'lZ00deAjUISs53+FEzZglRrASzr3WwVmSF3I4DkXvCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}