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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c70379a4d1f6f602721af22bfed1467379e7c4a2af7d5c99f92dfd20bf5161d' 
  AND token = 'jRVeI5mVZ810GIN/XAbR4BpDTU/dLzqY/rvEjps2jj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}