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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98194e980880469942011fe60a2612cf276b8eb4969cd88198859050c3c596e7' 
  AND token = 'CRNxZh1cgewR2VD8bXLrT/yAFFUGoUqRBnhwEZVTOeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}