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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099dbe687356a46dc60bf3142b07e4df772cb0b088bd9df7329cd57553b9e222' 
  AND token = 'I0MHQ4lf5S4k5qNvdLMNwmHb1luGOVALSNOfslh8/Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}