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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f20586611e3da64096fa67e48970763cf30596dea478a427c22e7bad7b6448e9' 
  AND token = '13l8CIzMXpG/k+XTDeA75NREXSsDl5OIRwMAu50YaDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}