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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c761aeb5404d7442b4dd009d950a91cfeb72787b04a7a088e00f8b7dc51ed7' 
  AND token = 'QZ9XPMZRwRS/Cbya1r8dpj4/KaNSz9SO8o1dK14aOws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}