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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dde55649ee2c68c10ef75e1fa5a4ff9d317616893cfdfaef1d7b399b56097ae8' 
  AND token = 'I1fm9qwUgT7cOZMMv3itCyA/f8oJsMYY+fSmVFEJ2GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}