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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd454e3cd33fba91e7ccd1becccaee0afb9192c7a5290a189f19812491a8d94a7' 
  AND token = '8P9MP8zIDMfg3WkViKeFv64m5cMrP6ZFP/9MT2QvHXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}