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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86273b234187ec6fd80504e1273dbcb3ee53109f4d9911f13365c3a806317c3' 
  AND token = '+IkdkgUiuuHZ74jTdnojtoAFL1WedbPGNRineUuF4J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}