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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdcd0c44e7e44801153ce39d3a2ca812dc102866e1ecbfa123458825d063a00' 
  AND token = 'skC0uAA9y5fNifxa+GUEwCLjZ2hsbE6/jfdOD9rNOEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}