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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '524be1ab612866c0257d64636f871fe1f64ccc796bd94b60cb40748cb6b3464d' 
  AND token = 'kEt+xmPVDhvmCKA0H/wo0t+Tqdxa2msqzSDhzEcn0lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}