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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d1a1c3dc7fa77c8071a67fa15a337e1d352c0eb21ffde3dd2546a4472220cc6' 
  AND token = 'xVwSQqOeQNSg3X8iCDDXFxgfHGuJ9G9lV7ljOsQj2wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}