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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c5d0912467c64ded5522e8804aff5cdd46bc0f80c610bbb8d3ce984d6b0010' 
  AND token = 'TUNzF3fFSnlQZCYVR+uMyppizwQTEbfo3+1wjmH9zJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}