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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23553f3a012cbc748efc39a1ac4e7e2f89c596d3a3151e9062add12258237d71' 
  AND token = 'HEPGdzKkDCwYacvkVFt/gQ/WisOCfIcCtwfhu1UN0Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}