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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af68af344fda3fdff8be5e7ed965ddbf53c9b916548b134798586c3d37aa20ac' 
  AND token = 'N+exVYDu0EAMpm1QZ4r6TllOr3ER3WflbT5cc4IeQo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}