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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39e3f9d337de349df450c599e785806021422c3b8919fc05e567e03ee764258' 
  AND token = 'SFHuJ0p+tUHnkqnvhI0snXLX/Z0o+FCQb0lPjOp+No4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}