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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b0d5a61037ac51a442be7deebbb12738b637aed575b5ef025fb2f8ddb83037' 
  AND token = 'fnqaXUvhoc83cmmNapY3u/5wLBbRJExbUgRHkRPMu4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}