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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4449ffe6596acf4ed21a1ffc69e0a1d6ee004069a08e1c23ff0bbe11d82cc57f' 
  AND token = 'ilcUIv8cdEH0YdwAQzVQjig/Z+5cE/Fp8e0FtNLU5Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}