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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8126bc4881f41cf15b9217a09625685f6b3d5940c3ba502f6b3810683f0ebe40' 
  AND token = '4Vk/05oU3dScM2mnilyg46q9mqxJdJOyekYh6O8yva4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}