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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43823241818013e968058b61d6462796f9b8ead9b658e5a49ccef30e3bd56ad8' 
  AND token = '6kcD0ESzjVFpgk2d3BKvAibhb0Q3FxnovP5kw3nu0oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}