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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfaefccc2394640c68b58c37f82413d23241622ad0a06e591dad75e0e7f06364' 
  AND token = 'uoSbymjxAonF8eQW/Uk+bbMLUoH/OKe5D80LJZU2InI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}