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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49560f5b605cd8ac805ae7df73847810592a25058be0845cd71f4907c27f5f29' 
  AND token = '7dK+virZPkojeIHJ544o20vffe0Bip64ozF97dU5ToM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}