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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64dba02b0967dfd68754929695b2c85a64f0939d4308237aafe680f15f5bc66' 
  AND token = 'y+colDbhHTBGXYngmONceObJGzjfE9ADrcfn3rcA790=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}