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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1282b342225482e0731d83fd47decbb6f18df55fc1b9bc699d0e91b38e035e58' 
  AND token = 'lWZxKAE7RduUVLyy9E+DA5HM2EBXk96J5mZBAMnNRTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}