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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cdae6b9501f29825a8eeb87d6c801d8d0e6ea49783d76768c0dce826029affe' 
  AND token = 'YDuhf1G5pW1PrF/l2p+W/LNJtq1Xmm1Hl+o6eAt5XoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}