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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f109eba1518bb7117d34d5305fa1b7c2e388db21448131bcad3be16d500c4aa' 
  AND token = 'cW+ihj0Q4BgsJCCf2pwQhKc/ELe6Ae9KWfV4VZFdYZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}