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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d6673ce9bc9b3be5910748940294d3b12ee1c051a52af42d8a39c003aeac72' 
  AND token = '3LG/cs0vpq1Qt7xwvjnOMKbPj+7hKTFRZOMdvX7R9eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}